Relationship between thyroid disorder and iron deficiency anaemia in pregnancy

Relationship between thyroid disorder and iron deficiency anaemia in pregnancy

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Background: Thyroid disorders and iron deficiency (ID) are associated with obstetrical and fetal complications.Iron is essential for the normal functioning of thyroid peroxidase (TPO-abs) and ID is frequent during pregnancy.Objective: The present study was undertaken to see the relationship between iron deficiency anaemia and thyroid disorder in antenatal cases.Methods: A total of 100 cases attending the outpatient department of Obstetrics and Gynecology in their 1st trimester (from LMP to 12 weeks) were studied at Naval Hospital Powai during a period from Jan 2016 to Dec 2017.A detailed clinical and obstetric history was taken and patients were subjected to routine antenatal investigations along with thyroid profile.

Results: Among 100 cases, 21 antenatal cases had increased TSH.Out of which 4 bolia outlet gent cases had overt hypothyroidism and 17 cases had subclinical hypothyroidism.2 cases had decreased thyroid stimulating hormone in early trimester out of which only 1 had overt hyperthyroidism.In the same study 23 cases had mild iron deficiency anaemia and 4 had moderate anaemia.It was later correlated that out of 27 cases with anaemia 14 had hypothyroidism.

51% of equi-jec 6 the cases with anaemia had hypothyroidism and 60% of the hypothyroid cases had iron deficiency anaemia.Applying regression analysis between TSH and Hb level, there was a positive correlation between these two factors in cases.r2 value was found to be 0.2871.This was statistically significant with a P value of less than 0.

005.Conclusion: It is concluded that there is increased prevalence of thyroid disorders and iron deficiency anaemia in antenatal cases and there is relationship between iron deficiency anaemia and hypothyroid cases.